Driven by its simplicity, low-cost, high sensitivity, and utility, carbon-based optical
biosensors have been extensively researched as an alternative tool to aid scientists in
identifying environmental pollutants and important biomolecules. The main focus of this
doctoral research work is to design metal doped carbon quantum dots sensors, sensing
protocols, and to explore the practical applications of these sensors in the detection of the
analytes in aqueous medium, real samples and model plant or living organisms. We have
synthesized Mn doped CD(Mn-CD), Ag-doped CD(Ag-CD), and biosource derived carbon
dot for the detection of environmental pollutants arsenic and organoarsenic compounds,
perchlorate, hexavalent Cr(VI). All these sensor probes can selectively detect the intended
analyte in aqueous medium and plant samples. Further due to good translocation properties
these sensor nanoprobes have been used to detect heavy metals in different parts of the plants
through confocal imaging. In the direction of biomarker detection we have developed 2 metal
integrated carbon dots for detection of glycine, dopamine and Ca2+ in sweat. Due the unique
combination of fluorescence property of CD, conductance property along with molecular
recognition, these sensors can detect analytes in both fluorescence and electrochemical mode.
The details of our effort have been discussed in respective chapters.