Course Details
Subject {L-T-P / C} : CY3106 : Purifications and Characterizations of Organic Compounds { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Rupam Dinda
Syllabus
Chromatography: Adsorption chromatography, Partition chromatography, Paper chromatography, Thin-layer chromatography, column chromatography, gas-liquid chromatography, ion-exchange chromatography.
Spectroscopic techniques of characterization: UV-Vis spectroscopy (Basic principle, instrumentation, characteristic absorptions of organic compounds, IR Spectroscopy (Basic principle, instrumentation, modes of vibration, absorption trends, analysis of IR sprctrum), NMR Spectroscopy (1H NMR, Basic principle, chemical shift and shielding, instrumentation, chemical equivalence, magnetic equivalence, spin-spin coupling, NMR spectrum of simple organic compounds), Mass-spectrometry (Basic Principle, instrumentation, ionization methods, fragementation, molecular ion peak, metastable peak, McLafferty rearrangement, nitrogen rule, Mass analysis of simple compounds). Comprehensive problems on structure elucidation of small organic molecules.
Course Objectives
- To learn the basic principles of techniques used for purification and characterizations of organic compounds.
- To learn how to make structural assignments and characterization of organic compounds using various spectroscopic technologies, especially Mass, UV-Vis, IR, and 1H-NMR techniques
Course Outcomes
This course will help the students in understanding various techniques used for purification and characterization of mainly organic compounds (partly inorganic compounds too).
Essential Reading
- D. C. Pavia, G. M. Lampman, G. S. Kriz, Introduction to Spectroscopy, THOMSON , 3rd Edition, 2007
- R. K. Bansal, A text book of Organic Chemistry, New Age International Publisher , 5th Edition, 2007
Supplementary Reading
- B. H. Williams, I. Flemming, Spectroscopy Methods in Organic Chemistry, McGraw Hill , 2005
- Bessler and Silverstein, Spectroscopy of Organic Compounds, JOHN WILEY , 2001