National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : BM6544 : Advanced Biochemical Engineering { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Kasturi Dutta

Syllabus

Enzyme kinetics: First and order second order reactions Enzyme inhibition multi-substrate enzyme kinetics Multisite allosteric enzyme kinetics Enzyme immobilization Heterogeneous biochemical reaction systems, Reaction rates for immobilised enzymes, mass transfer in heterogeneous system Kinetic models for cell growth and product formation: unstructured, chemically structured and metabolic models. Transport phenomena in bioprocess Bioreactor design and analyses

Course Objectives

  • Knowledge of complex, mixed enzyme kinetics

Course Outcomes

1. Detail idea for the enzyme reaction kinetics, and inhibion studies. <br />2. Students will have detail idea about how mass transfer is affected in free and immobilized systems.

Essential Reading

  • J. E. Bailey and D. F. Ollis, Biochemical Engineering Fundamentals, McGraw-Hill Publishing Co. New York
  • Irwin H Segel, Biochemical Calculations, Wiley and sons

Supplementary Reading

  • P. M. Doran, Bioprocess Engineering principles, Academic Press,
  • M. L. Shuler and F. Kargi, Bioprocess Engineering- Basic concepts, Prentice Hall,