National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : BM2300 : Bioprocess Engineering - I { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Kasturi Dutta

Syllabus

Basic concepts of process calculations, Fundamentals of material and energy balance for processes with/without chemical reaction. Simultaneous mass and energy balance in flow and without flow conditions. Microbial growth, batch, fed-batch and continuous growth, Nutritional requirements for growth and product formation. Medium design and optimization. Types of sterilization, thermal death kinetics of microorganism. Heat sterilization of liquid medium in batch and continuous mode. Air sterilization. Different types of bioreactors, configuration of Bioreactors and their main components. Modes of bioreactor operation. Fermentaion definition, inoculum development. Various types of Fermentation, submerged fermentation, aerobic and anaerobic fermentation. Overview of biosynthetic mechanisms. Metabolic stoichiometry.

Course Objectives

  • Basic knowledge about bioprocessing of industrially important products

Course Outcomes

The students will be able to explain the bioprocessing of industry relevant products

Essential Reading

  • M. L. Shuler and F. Kargi, Bioprocess Engineering: Basic Concepts, Prentice Hall of India, 2001
  • J E Bailey and D F Ollis, Biochemical Engineering Fundamentals, Mc Graw & Hills Publication

Supplementary Reading

  • P.M. Doran, Bioprocess Engineering Principles, Academic Press, 2012
  • B.W. Blanch and D. S Clark, Biochemical Engineering, Marcel Dekker Inc