National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Faculty Profile

BIOGRAPHY

Dr. Bismita Nayak, Associate Professor and Head of the Department of Life Sciences at the National Institute of Technology (NIT) Rourkela, Odisha, is a distinguished scientist and educator with over 20 years of research experience. She earned her PhD from the Centre for Biomedical Engineering, IIT Delhi, in collaboration with AIIMS and the National Institute of Immunology (NII), New Delhi. As a Fulbright-Nehru Postdoctoral Fellow (2013-2014), she worked at MIT’s Department of Chemistry and Stanford School of Medicine’s Department of Genetics, gaining expertise in high-dimensional flow cytometry and immunological studies, including DNP-KLH epitopic immunosuppression in murine models. Dr. Nayak has published 49 peer-reviewed papers, 19 Indian conference papers, and 9 international conference papers. She has contributed to 8 book chapters and 6 forthcoming chapters with Springer. Her innovations include a patented “Biocompatible Gelatin and I-Carrageenan-Based Composite Hydrogel” and a pending patent on “Nanoformulation for Topical Skin Applications.” She has secured funding of approximately Rs. 120 lakhs from DST, SERB, and DBT for various projects. Her research focuses on Translational Regenerative Medicine, including bio-scaffolds for pancreatic islet transplantation and immunomodulatory vaccines for Type 1 Diabetes and cancers such as oral carcinoma, non-small cell lung carcinoma, and glioblastoma. She has explored mesenchymal stem cells, green-synthesized metallic nanoparticles, biomaterials, polymeric nanoparticles, cell-material interactions, and targeted delivery of therapeutic molecules. Passionate about innovation, she is integrating machine learning and artificial intelligence to optimize nanoparticles. Her expertise lies in immuno-engineering and nanoparticle-based drug/vaccine delivery for cancer and infectious diseases.

EXPERTISE INFORMATION

Research Group
  • Immunology and Molecular Medicine
Areas of Interest
  • Nanobiotechnology
  • Drug/Vaccine delivery
  • Tissue Engineering
  • Cancer Biology
  • Immunotherapy
  • Regenerative Medicine
  • AI Based Drug Design and Nanotherapeutics

Bismita Nayak
ବିସ୍ମିତା ନାୟକ Associate Professor & HOD (Life Science)

Life Science

nayakb@nitrkl.ac.in

0661 - 246 2682

25

PUBLICATIONS

3

SPONSORED PROJECTS

12

DOCTORAL STUDENTS

3

CONTINUING EDUCATION

PERSONAL INFORMATION

Bismita Nayak

Associate Professor

Life Science

Room Number: MN-341

Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

2008

Ph.D.
Preparation and Immunological evaluation of biodegradable particle-based Rotavirus vaccine.
Centre for Biomedical Engineering, Indian Institute of Technology Delhi & All India Institute of Medical Sciences, New Delhi

2002

M.Sc
Microbiology
Orissa University of Agriculture and Technology

1999

B.Sc (Hons)
Zoology
Ravenshaw Autonomous University

Teaching Experience
  • Immunology, Molecular Medicine,  National Institute of Technology Rourkela,   01 Dec 2008 - 31 Dec 2024
Post Doctoral Research Experience
  • Immunology and Nanobiotechnology,  Department of Genetics, Stanford School of Medicine,   28 Feb 2014 - 30 Sep 2014
  • Viscosity measurements of DNA and Protein & Biophysical Characterization,  Department of Chemistry, Massachusetts Institute of Technology Cambridge,   02 Sep 2013 - 28 Feb 2014

Development of efficient and stable non-viral vector based therapeutics for nucleic acid delivery. SERB
  • Principal Investigator
  • 36
  • Completed   Sponsored
Outer membrane vesicle proteins targeted as new vaccine strategies for vibrio cholerae through microparticulate delivery system SERB
  • Principal Investigator
  • 36
  • Completed   Sponsored
Utilization of mushroom extracts as prebiotic sources to develop synbiotic microcapsules SERB
  • Co-Investigator
  • 36
  • Completed   Sponsored

Total Publications: 25

D. Majhi, K. Das, R. Bariki, S. Padhan, A. Mishra, R. Dhiman, P. Dash, B. Nayak, and B. G. Mishra,"A facile reflux method for in situ fabrication of a non-cytotoxic Bi2S3/ß-Bi2O3/ZnIn2S4 ternary photocatalyst: a novel dual Z-scheme system with enhanced multifunctional photocatalytic activity", Journal of Materials Chemistry A, vol.303, pp.120902, Royal Society of Chemistry 2022, https://doi.org/10.1039/D0TA06129H       Article

S. Panda, B. C. Pattnayak, P. Dash, B. Nayak, and S. Mohapatra,"Papaya-Derived Carbon-Dot-Loaded Fluorescent Hydrogel for NIRStimulated Photochemotherapy and Antibacterial Activity", ACS applied polymer materials, vol.4, pp.369-380, ACS, December 2021, https://doi.org/10.1021/acsapm.1c01317       Article

K. Das, R. Bariki, S. K. Pradhan, D. Majhi, P. Dash, A. Mishra, R. Dhiman, B. Nayak, and B. G. Mishra,"Boosting the photocatalytic performance of Bi2Fe4O9 through formation of Z-scheme heterostructure with In2S3: Applications towards water decontamination", Chemosphere, vol.306, pp.135600, Elsevier B.V. 2022, https://doi.org/10.1016/j.chemosphere.2022.135600       Article

S. Mohapatra, S. Kumar, S. Kumar, A. K. Singh, and B. Nayak,"Immunodominant conserved moieties on spike protein of SARS-CoV-2 renders virulence factor for the design of epitope-based peptide vaccines", VirusDisease, vol.34, pp.456–482, Springer, November 2023, View Details       Article

S. K. Nayak, P. Dash, R. Bariki, S. K. Pradhan, S. Panda, B. Nayak, and B. G. Mishra,"Metal-Organic Framework-Derived Hierarchical Ag/Sr6Bi2O9-a-Bi2O3 Ternary Photocatalyst for Micropollutant Remediation and Bacterial Photoinactivation", ACS Applied Engineering Materials, vol.2, pp.179-194, ACS, January 2024, View Details       Article

The 3rd International Conference on Frontiers in Biological Sciences (InCoFIBS-2023) Life Science (Conference)
A national conference on PRESENT AND FUTURE OF DRUG DELIVERY APPROACHES AND MOLECULAR MEDICINE Life Science (Conference)
Advanced Techniques In Life Sciences (ATILS) 07 - 08 March 2013 Life Science (Short-term Course)

  • BM241 : Microbiology {Theory}
  • LS100 : Biology {Theory}
  • LS1001 : Biology {Theory}
  • LS301 : Embryology {Theory}
  • LS310 : Basics in Molecular Medicine {Theory}
  • LS3102 : Physiology {Theory}
  • LS3302 : Bioinstrumentation {Theory}
  • LS3303 : Biophysics {Theory}
  • LS3406 : Molecular Basis of Development {Theory}
  • LS403 : Immunology {Theory}
  • LS405 : Cell Biology {Theory}
  • LS406 : Immunotechniques {Theory}
  • LS410 : Food Science {Theory}
  • LS4104 : Molecular Biology {Theory}
  • LS4603 : Enzymology and Metabolism {Theory}
  • LS512 : Developmental Biology {Theory}
  • LS522 : Genetics {Theory}
  • LS532 : Molecular Medicine {Theory}
  • LS535 : Basics in Molecular Medicine {Theory}
  • LS5410 : Molecular Genetics {Theory}
  • LS5414 : Systems Physiology {Theory}
  • LS5502 : Immunotechniques {Theory}
  • LS551 : Bioenergetics {Theory}
  • LS6010 : Molecular Medicine {Theory}
  • LS610 : Molecular Medicine {Theory}
  • LS3093 : Life Science Laboratory- III {Practical}
  • LS3094 : Life Science Laboratory- IV {Practical}
  • LS371 : Embryology Laboratory {Practical}
  • LS474 : Immunotechniques Laboratory {Practical}
  • LS474 : Immunotecniques Laboratory {Practical}
  • LS475 : Immunology Laboratory {Practical}
  • LS4881 : Research Practice {Practical}
  • LS5591 : Immunology Laboratory {Practical}

Ph.D. Students [12]
Development of a Novel Fluorescent and Injectable Thermosensitive Hydrogel as Multifunctional Modalities for Imaging and Glioblastoma Therapy
Priyanka Dash
Enrolled: Jul 2017
Graduated :  Oct 2024
Supervisor
Establishment of Caprine Pancreas Derived Extracellular Matrix as a Novel Reservoir to Develop Xenotransplantable Organ and Scarless Wound Healing Hydrogel
Garima Singh
Enrolled: Jul 2017
Graduated :  Oct 2024
Supervisor
Ethosomal Nano-Carriers Encapsulating Novel Green Synthesized AgNPs and Sericin Protein as Potential Therapeutics against Skin Carcinoma
Debasis Nayak
Enrolled: Jul 2012
Graduated :  May 2018
Supervisor
Immunological Evaluation of Biodegradable Particle based Nanoparticles Encapsulating OMP Antigen As Potential Vaccine Candidate
Pradipta Ranjan Rauta
Enrolled: Jan 2011
Graduated :  Dec 2016
Supervisor
Elucidating the Berberine-Induced Epigenetic Regulation of Nrf2 Signaling Axis and Its Targeted Delivery via Folate-Functionalized Bovine Serum Albumin Nanocarriers against Glioblastoma
Sayantan Ghosh
Enrolled: Jul 2019
Thesis Submitted
Supervisor
Understanding the underlying mechanism of hyperglycemic bone degeneration and their innovative therapeutic treatment approaches
Sarbani Ashe
Enrolled: Jul 2012
Thesis Submitted
Supervisor
Cancer Biology
Yamini Prashanti Patnaik
Enrolled: Jul 2024
Continuing
Supervisor
Nanoparticle Based Drug Delivery system
Swastik Arya
Enrolled: Jul 2024
Continuing
Supervisor
Tissue Engineering, Molecular Immunology
Manav Goenka
Enrolled: Jul 2024
Continuing
Co-Supervisor
Cancer biology and Immunology
Reetika Rani
Enrolled: Aug 2021
Continuing
Supervisor
IMMUNOLOGY, MOLECULAR MEDICINE
Subhashree Mohapatra
Enrolled: Jan 2020
Continuing
Supervisor
Immunology
Puja Das
Enrolled: Jul 2019
Continuing
Supervisor

Awards And Honours
  • USIEF Fulbright Nehru Postdoctoral Fellowship Award for year 2013-2014 at Stanford, School of Medicine,   2013
Memberships / Fellowships
  • Life Member, Indian Immunological Society, India,   2009
  • Life member of Society of Biomaterials and Artificial Organs,   2007