BIOGRAPHY
Prof. Bibekanand Mallick is a Fellow of the National Academy of Biological Sciences (NABS) and a Member of the National Academy of Sciences, India (NASI). He is the editor of reputed SCI journals, including Gene and Communications Biology (Nature portfolio journal). Prof. Mallick leads the RNAi Laboratory at the National Institute of Technology Rourkela and conducts a wide range of research in molecular biology in cancer. He is known for his research on RNA interference, gene silencing, drug repurposing, and RNAi therapeutics for cancer. He has discovered a small RNA that potentially suppresses tumorigenesis and reduces chemotherapy resistance in cancers, especially tongue cancer. He is also the author of several books published by renowned publishers like Oxford University Press, McGraw Hill, Springer, and Elsevier, USA.
EXPERTISE INFORMATION
Research Group
- Bioinformatics
Areas of Interest
- RNAi, Cancer biology, Next-gen Seq, Molecular biology
77
PUBLICATIONS7
SPONSORED PROJECTS17
DOCTORAL STUDENTS2
CONTINUING EDUCATIONPERSONAL INFORMATION
Bibekanand Mallick
Professor
Life Science
Room Number: MN-342
Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008
Ph.D. (IACS, Kolkata)
Laboratory Development
- RNAi and Functional Genomics Lab., DST, DBT, CSIR, ICMR & NIT Rourkela, This lab is dedicated for executing research to decrypt the role of regulatory non-coding RNAs (miRNA, piRNA, lncRNA) as well as their crosstalks in cancer and neurodegenerative diseases by employing molecular biology approaches.
SNP mediated changes in the structure of VPS26A mRNA and its implication in the actiology of Diabetes. ICMR
- Co-Investigator
- 36
- Running Sponsored
Identification of new drug(s) for treating Endometriosis-Associated Infertility by drug repurposing using signature MicroRNAs. ICMR
- Principal Investigator
- 36
- Completed Sponsored
Genomewide profiling of PIWI0interacting RNAs (piRNAs) by Next-Generation Sequencing and investigating their role in Oral Squamous Cell Carcinoma. DBT, Govt Of India
- Principal Investigator
- 36
- Completed Sponsored
Identification of piRNA associated genomic and epigenomic regulatory networks in ovarian cancer DST
- Principal Investigator
- 36
- Completed Sponsored
Structural impact of SNPs on miRNA-mediated regulation and its implication in Cancer (RGYI) DBT
- Principal Investigator
- 36
- Completed Sponsored
Decoding the Dominant Microrna-Mediated Pluripotency Networks in Stem Cells CSIR
- Principal Investigator
- 36
- Completed Sponsored
Integration Polymorphisms and NGS in dissecting complex networks of mi RNA-mediated regulation in neurodegenerative diseases DST
- Principal Investigator
- 36
- Completed Sponsored
Total Publications: 77
B. Das, N. Jain, and B. Mallick,"piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair", Communications Biology, vol.4, no.1312, pp.1-18, Nature 2021, 10.1038/s42003-021-02844-1 Article
D. Samantarrai and B. Mallick,"miR-429 inhibits metastasis by targeting KIAA0101 in Soft Tissue Sarcoma", Experimental Cell Research, vol.357, no.1, pp.33-39, Elsevier 2017, 10.1016/j.yexcr.2017.04.017 Article
C. Liu, B. Mallick, D. Long, W. Rennie, A. Wolenc, C. S. Carmack, and Ye. Ding,"CLIP-based prediction of mammalian microRNA binding sites", Nucleic Acids Research, vol.41, no.14, pp.e138, Oxford Academic, May 2013, 10.1093/nar/gkt435 Article
B. Das, N. Jain, and B. Mallick,"Ribonucleotide reductase subunit M2 is a potential prognostic marker and therapeutic target for soft tissue sarcoma", Gene, vol.808, no.145988, pp.1-14, Elsevier, January 2022, 10.1016/j.gene.2021.145988 Article
B. Mallick,"Biology for Engineers", McGraw Hill, September 2021 Book
WORKSHOP ON “MOLECULAR AND GENOMIC TECHNIQUES IN CELLULAR STUDIES (MAGTICS - 2024)" Life Science (Workshop)
- Coordinator
- 02 Sep 2024 - 06 Sep 2024
- Brochure
WORKSHOP ON “MOLECULAR AND GENOMIC TECHNIQUES IN CANCER STUDIES (MAGTICS - 2023)" Life Science (Workshop)
- Coordinator
- 24 Jul 2023 - 28 Jul 2023
- Brochure
- BM343 : Bioinformatics {Theory}
- BM368 : Bioinformatics {Theory}
- BM651 : Advanced Bioinformatics {Theory}
- LS100 : Biology {Theory}
- LS1001 : Biology {Theory}
- LS310 : Basics in Molecular Medicine {Theory}
- LS402 : Bioinformatics {Theory}
- LS403 : Immunology {Theory}
- LS405 : Cell Biology {Theory}
- LS420 : Applied Bioinformatics {Theory}
- LS4201 : Bioinformatics {Theory}
- LS509 : System Physiology {Theory}
- LS536 : RNAi, Stem cells & Oncogenomics {Theory}
- LS5414 : Systems Physiology {Theory}
- LS6001 : Advanced Bioinformatics {Theory}
- LS601 : Advanced Bioinformatics {Theory}
- BM370 : Bioinformatics Laboratory {Practical}
- BM376 : Bioinformatics and Drug Design Laboratory {Practical}
- BM386 : Bioinformatics Laboratory {Practical}
- BM674 : Bioinformatics Laboratory {Practical}
- LS275 : Computational Biology Laboratory - I {Practical}
- LS377 : Computational Biology Laboratory – II {Practical}
- LS4291 : Bioinformatics Laboratory {Practical}
- LS472 : Bioinformatics Laboratory {Practical}
- LS478 : Computational Nucleic acids and Proteins Laboratory {Practical}
- LS4881 : Research Practice {Practical}
- LS573 : Computer aided Drug Design Laboratory {Practical}
- LS575 : Applied Bioinformatics Laboratory {Practical}
Ph.D. Students [17]
New Insights into the Regulatory Functions and Mechanisms of Action of MicroRNA-197 Duo in the Pathophysiology of Human Fibrosarcoma
Neha JainEnrolled: Jul 2016Graduated : Dec 2021Supervisor
Investigating the microRNA-mediated Target Regulations Associated with Metastasis of Cancer: Special Focus on Soft Tissue Sarcoma and Breast Carcinoma
Devyani SamantarraiEnrolled: Jul 2012Graduated : Feb 2017Supervisor
Identification of Potential Therapeutic Targets and Investigating Piwi-Interacting RNA (piRNA)-Mediated Target Regulations Implicated in Oncogenesis and Drug Resistance of Sarcoma
Basudeb DasEnrolled: Jul 2016Graduated : Feb 2022Supervisor
Investigation of Ppotential piRNA-mediated Regulation of Oncogenicity and Chemoresistance Imparted by FDFT1 in the Pathophysiology of Tongue Squamous Cell Carcinoma
Trisha ChattopadhyayEnrolled: Jan 2019Graduated : Feb 2024Supervisor
Regulatory Non-Coding RNAs as Cellular Rheostats: Modulating Biological Functions to Pathophysiology of Diseases
Jyoti RoyEnrolled: Jan 2015Graduated : Jun 2019Supervisor
Prediction of Repurposed Drug to Neutralize the Effects of Non-coding RNAs and Their Targets in Glioblastoma Oncogenesis: A Gene Expression and Molecular Simulation Approach
Rojalin NayakEnrolled: Jul 2018Graduated : May 2024Supervisor
Profiling of DNA Methylation and Single Nucleotide Polymorphism For Diagnosis, Prognosis and Targeting DNA Methyltransferase For Therapeutic Intervention of Breast Cancer
Arunima ShilpiEnrolled: Jul 2011Graduated : Nov 2016Co-Supervisor
Deciphering Transcriptional and Post-transcriptional Regulation of Genes Modulating Stem Cell Pluripotency and Differentiation Networks
Mousumi SahuEnrolled: Jul 2013Graduated : Nov 2018Supervisor
Genome-wide Identification and Characterization of Features of the Piwi-Interacting RNAs and Targets
Garima SinghEnrolled: Jul 2014Graduated : Oct 2021Supervisor
Food microbiology
Karthika Parvathy K REnrolled: Jan 2018ContinuingSupervisor
RNAi & MOLECULAR BIOLOGY
Pooja GuptaEnrolled: Jul 2019ContinuingSupervisor
RNAi and disease biology
Priyajit BiswalEnrolled: Aug 2021ContinuingSupervisor
RNAi and disease biology
Anthony LalruatfelaEnrolled: Aug 2021ContinuingSupervisor
RNAi and CANCER BIOLOGY
Subham Kumar BeheraEnrolled: Aug 2022ContinuingSupervisor
CANCER BIOLOGY AND MOLECULAR BIOLOGY
Sruti BiswalEnrolled: Jan 2023ContinuingSupervisor
RNAi and Cancer biology
Jiban Jyoti DashEnrolled: Jul 2024ContinuingSupervisor
CANCER BIOLOGY
Deepak Kumar BeheraEnrolled: Aug 2024ContinuingSupervisor
Awards And Honours
- Editor, Communications Biology (Nature portfolio journal), 2022
- Associate Editor, GENE, 2021
- Editor, Scientific Reports (Nature portfolio journal), 2015
Memberships / Fellowships
- Fellow, National Academy of Biological Sciences, 2023
- MNASc (Member, National Academy of Sciences, India), 2015
- Life Member, National Academy of Biological Sciences, India, 2013
- Life Member, Indian Association for Cancer Research, 2012
- Life Member, Biotech Research Society, 2012
- Life Member, The Indian Science Congress Association, India, 2011
- Member, New York Academy of Sciences, USA, 2009