National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Faculty Profile

BIOGRAPHY

Prof. Bibekanand Mallick is a Fellow of the National Academy of Biological Sciences (NABS) and a Member of the National Academy of Sciences, India (NASI). He is the editor of reputed SCI journals, including Gene and Communications Biology (Nature portfolio journal). Prof. Mallick leads the RNAi Laboratory at the National Institute of Technology Rourkela and conducts a wide range of research in molecular biology in cancer. He is known for his research on RNA interference, gene silencing, drug repurposing, and RNAi therapeutics for cancer. He has discovered a small RNA that potentially suppresses tumorigenesis and reduces chemotherapy resistance in cancers, especially tongue cancer. He is also the author of several books published by renowned publishers like Oxford University Press, McGraw Hill, Springer, and Elsevier, USA.

EXPERTISE INFORMATION

Research Group
  • Bioinformatics
Areas of Interest
  • RNAi, Cancer biology, Next-gen Seq, Molecular biology

Bibekanand Mallick Professor

Life Science

mallickb@nitrkl.ac.in

0661 - 246 2685

77

PUBLICATIONS

7

SPONSORED PROJECTS

17

DOCTORAL STUDENTS

2

CONTINUING EDUCATION

PERSONAL INFORMATION

Bibekanand Mallick

Professor

Life Science

Room Number: MN-342

Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

Ph.D. (IACS, Kolkata)

Laboratory Development
  • RNAi and Functional Genomics Lab.,  DST, DBT, CSIR, ICMR & NIT Rourkela,   This lab is dedicated for executing research to decrypt the role of regulatory non-coding RNAs (miRNA, piRNA, lncRNA) as well as their crosstalks in cancer and neurodegenerative diseases by employing molecular biology approaches.

SNP mediated changes in the structure of VPS26A mRNA and its implication in the actiology of Diabetes. ICMR
  • Co-Investigator
  • 36
  • Running   Sponsored
Identification of new drug(s) for treating Endometriosis-Associated Infertility by drug repurposing using signature MicroRNAs. ICMR
  • Principal Investigator
  • 36
  • Completed   Sponsored
Genomewide profiling of PIWI0interacting RNAs (piRNAs) by Next-Generation Sequencing and investigating their role in Oral Squamous Cell Carcinoma. DBT, Govt Of India
  • Principal Investigator
  • 36
  • Completed   Sponsored
Identification of piRNA associated genomic and epigenomic regulatory networks in ovarian cancer DST
  • Principal Investigator
  • 36
  • Completed   Sponsored
Structural impact of SNPs on miRNA-mediated regulation and its implication in Cancer (RGYI) DBT
  • Principal Investigator
  • 36
  • Completed   Sponsored
Decoding the Dominant Microrna-Mediated Pluripotency Networks in Stem Cells CSIR
  • Principal Investigator
  • 36
  • Completed   Sponsored
Integration Polymorphisms and NGS in dissecting complex networks of mi RNA-mediated regulation in neurodegenerative diseases DST
  • Principal Investigator
  • 36
  • Completed   Sponsored

Total Publications: 77

B. Das, N. Jain, and B. Mallick,"piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair", Communications Biology, vol.4, no.1312, pp.1-18, Nature 2021, 10.1038/s42003-021-02844-1       Article

D. Samantarrai and B. Mallick,"miR-429 inhibits metastasis by targeting KIAA0101 in Soft Tissue Sarcoma", Experimental Cell Research, vol.357, no.1, pp.33-39, Elsevier 2017, 10.1016/j.yexcr.2017.04.017       Article

C. Liu, B. Mallick, D. Long, W. Rennie, A. Wolenc, C. S. Carmack, and Ye. Ding,"CLIP-based prediction of mammalian microRNA binding sites", Nucleic Acids Research, vol.41, no.14, pp.e138, Oxford Academic, May 2013, 10.1093/nar/gkt435       Article

B. Das, N. Jain, and B. Mallick,"Ribonucleotide reductase subunit M2 is a potential prognostic marker and therapeutic target for soft tissue sarcoma", Gene, vol.808, no.145988, pp.1-14, Elsevier, January 2022, 10.1016/j.gene.2021.145988       Article

B. Mallick,"Biology for Engineers", McGraw Hill, September 2021       Book

WORKSHOP ON “MOLECULAR AND GENOMIC TECHNIQUES IN CELLULAR STUDIES (MAGTICS - 2024)" Life Science (Workshop)
WORKSHOP ON “MOLECULAR AND GENOMIC TECHNIQUES IN CANCER STUDIES (MAGTICS - 2023)" Life Science (Workshop)

  • BM343 : Bioinformatics {Theory}
  • BM368 : Bioinformatics {Theory}
  • BM651 : Advanced Bioinformatics {Theory}
  • LS100 : Biology {Theory}
  • LS1001 : Biology {Theory}
  • LS310 : Basics in Molecular Medicine {Theory}
  • LS402 : Bioinformatics {Theory}
  • LS403 : Immunology {Theory}
  • LS405 : Cell Biology {Theory}
  • LS420 : Applied Bioinformatics {Theory}
  • LS4201 : Bioinformatics {Theory}
  • LS509 : System Physiology {Theory}
  • LS536 : RNAi, Stem cells & Oncogenomics {Theory}
  • LS5414 : Systems Physiology {Theory}
  • LS6001 : Advanced Bioinformatics {Theory}
  • LS601 : Advanced Bioinformatics {Theory}
  • BM370 : Bioinformatics Laboratory {Practical}
  • BM376 : Bioinformatics and Drug Design Laboratory {Practical}
  • BM386 : Bioinformatics Laboratory {Practical}
  • BM674 : Bioinformatics Laboratory {Practical}
  • LS275 : Computational Biology Laboratory - I {Practical}
  • LS377 : Computational Biology Laboratory – II {Practical}
  • LS4291 : Bioinformatics Laboratory {Practical}
  • LS472 : Bioinformatics Laboratory {Practical}
  • LS478 : Computational Nucleic acids and Proteins Laboratory {Practical}
  • LS4881 : Research Practice {Practical}
  • LS573 : Computer aided Drug Design Laboratory {Practical}
  • LS575 : Applied Bioinformatics Laboratory {Practical}

Ph.D. Students [17]
New Insights into the Regulatory Functions and Mechanisms of Action of MicroRNA-197 Duo in the Pathophysiology of Human Fibrosarcoma
Neha Jain
Enrolled: Jul 2016
Graduated :  Dec 2021
Supervisor
Investigating the microRNA-mediated Target Regulations Associated with Metastasis of Cancer: Special Focus on Soft Tissue Sarcoma and Breast Carcinoma
Devyani Samantarrai
Enrolled: Jul 2012
Graduated :  Feb 2017
Supervisor
Identification of Potential Therapeutic Targets and Investigating Piwi-Interacting RNA (piRNA)-Mediated Target Regulations Implicated in Oncogenesis and Drug Resistance of Sarcoma
Basudeb Das
Enrolled: Jul 2016
Graduated :  Feb 2022
Supervisor
Investigation of Ppotential piRNA-mediated Regulation of Oncogenicity and Chemoresistance Imparted by FDFT1 in the Pathophysiology of Tongue Squamous Cell Carcinoma
Trisha Chattopadhyay
Enrolled: Jan 2019
Graduated :  Feb 2024
Supervisor
Regulatory Non-Coding RNAs as Cellular Rheostats: Modulating Biological Functions to Pathophysiology of Diseases
Jyoti Roy
Enrolled: Jan 2015
Graduated :  Jun 2019
Supervisor
Prediction of Repurposed Drug to Neutralize the Effects of Non-coding RNAs and Their Targets in Glioblastoma Oncogenesis: A Gene Expression and Molecular Simulation Approach
Rojalin Nayak
Enrolled: Jul 2018
Graduated :  May 2024
Supervisor
Profiling of DNA Methylation and Single Nucleotide Polymorphism For Diagnosis, Prognosis and Targeting DNA Methyltransferase For Therapeutic Intervention of Breast Cancer
Arunima Shilpi
Enrolled: Jul 2011
Graduated :  Nov 2016
Co-Supervisor
Deciphering Transcriptional and Post-transcriptional Regulation of Genes Modulating Stem Cell Pluripotency and Differentiation Networks
Mousumi Sahu
Enrolled: Jul 2013
Graduated :  Nov 2018
Supervisor
Genome-wide Identification and Characterization of Features of the Piwi-Interacting RNAs and Targets
Garima Singh
Enrolled: Jul 2014
Graduated :  Oct 2021
Supervisor
Food microbiology
Karthika Parvathy K R
Enrolled: Jan 2018
Continuing
Supervisor
RNAi & MOLECULAR BIOLOGY
Pooja Gupta
Enrolled: Jul 2019
Continuing
Supervisor
RNAi and disease biology
Priyajit Biswal
Enrolled: Aug 2021
Continuing
Supervisor
RNAi and disease biology
Anthony Lalruatfela
Enrolled: Aug 2021
Continuing
Supervisor
RNAi and CANCER BIOLOGY
Subham Kumar Behera
Enrolled: Aug 2022
Continuing
Supervisor
CANCER BIOLOGY AND MOLECULAR BIOLOGY
Sruti Biswal
Enrolled: Jan 2023
Continuing
Supervisor
RNAi and Cancer biology
Jiban Jyoti Dash
Enrolled: Jul 2024
Continuing
Supervisor
CANCER BIOLOGY
Deepak Kumar Behera
Enrolled: Aug 2024
Continuing
Supervisor

Awards And Honours
  • Editor, Communications Biology (Nature portfolio journal),   2022
  • Associate Editor, GENE,   2021
  • Editor, Scientific Reports (Nature portfolio journal),   2015
Memberships / Fellowships
  • Fellow, National Academy of Biological Sciences,   2023
  • MNASc (Member, National Academy of Sciences, India),   2015
  • Life Member, National Academy of Biological Sciences, India,   2013
  • Life Member, Indian Association for Cancer Research,   2012
  • Life Member, Biotech Research Society,   2012
  • Life Member, The Indian Science Congress Association, India,   2011
  • Member, New York Academy of Sciences, USA,   2009