National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Faculty Profile

BIOGRAPHY

Dr. Mukesh Kumar Gupta is a Fellow of the Royal Society of Biology (UK), National Academy of Agricultural Sciences (NAAS), National Academy of Dairy Sciences (NADS), National Academy of Biological Sciences (NABS), National Academy of Environmental Sciences (NAES), Indian Association for Advancement of Veterinary Research (IAAVR), Academy of Environment and Life Sciences (AELS) and Society of Applied Biotechnology (SAB). He is an Executive Member of the Council of Asian Science Editors (CASE), HERITAGE Network (France), and Editorial Board Member of a few SCI-indexed Journals. He is a Board Member of the Animal Welfare Board of India (AWBI), Govt. of India, and Committee for Control and Supervision of Experiments on Animals (CCSEA), Ministry of Fisheries, Animal Husbandry and Dairying, Govt. of India. He is known for his research on animal cloning, transgenics, in vitro spermatogenesis by tissue engineering, a quick method to detect DNA fragmentation, and solid surface vitrification. His work on modified solid surface vitrification is used worldwide for the cryopreservation of pig oocytes and embryos, algae, microalgae, and plant cells. He is a Subject Expert of Biotechnology and Biomedical Engineering for the All India Council for Technical Education (AICTE), the National Testing Agency (NTA), and the National Board of Accreditation (NBA). He is currently on lien to the Indian Council of Medical Research (ICMR) as Director of the National Animal Resource Facility for Biomedical Research (NARFBR), Hyderabad.

EXPERTISE INFORMATION

Research Group
  • Tissue Engineering and Biomaterials
Areas of Interest
  • Gene Manipulation for Animal Transgenesis
  • Male Germ-line Stem Cells
  • Assisted Reproductive Technologies (IVF, ICSI, PGD, TESE, Assisted Hatching)
  • Tissue Engineering (Reproductive)
  • Cryopreservation of Gamete and Embryos
  • Bioinformatics & Computational Biology

Mukesh Kumar Gupta Professor

Biotechnology and Medical Engineering

guptam@nitrkl.ac.in

0661 - 246 2294

125

PUBLICATIONS

12

SPONSORED PROJECTS

8

DOCTORAL STUDENTS

6

CONTINUING EDUCATION

PERSONAL INFORMATION

Mukesh Kumar Gupta

Professor

Biotechnology and Medical Engineering

Room Number: BM-209

Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

2007

Ph.D.
Production of Transgenic Cloned Animals by Somatic Cell Nuclear Transfer
Konkuk University, Seoul, South Korea

Teaching Experience
  • Biotechnology and Medical Engineering,  National Institute of Technology Rourkela, India,   19 Dec 2011 - Continue
  • Animal Bioscience and Biotechnology,  Konkuk University, Seoul, South Korea,   01 Mar 2007 - 16 Dec 2011
Laboratory Development
  • Bioinformatics Laboratory,  National Institute of Technology Rourkela,   Big Data Analysis, Bioinformatics, Computational Biology
  • Gene Manipulation Laboratory,  National Institute of Technology Rourkela,   Recombinant protein production, gene manipulation in stem cells, transgenic animal production, male germline stem cells.
  • Center for Animal Bioinformatics and Computational Biology,  National Institute of Technology Rourkela,   Big Data Analytics, Software Development, Database Development, Multi-omics for infertility and production diseases in Animals

Establishment of Bioinformatics and Computational Biology Centre: Animal Bioinformatics - BIC at National Institute of Technology Rourkela DBT
  • Principal Investigator
  • 60
  • Running   Sponsored
Establishment of Bioinformatics and Computational Biology Centre: Animal Bioinformatics - BIC at National Institute of Technology Rourkela DBT
  • Principal Investigator
  • 60
  • Running   Sponsored
Development of an injectable hemostatic device for non-compressible hemorrhage. ICMR
  • Co-Investigator
  • 36
  • Running   Sponsored
First clotting clinical grade hemostatic agent for emergency care SERB
  • Co-Investigator
  • 36
  • Completed   Sponsored
In-Vitro spermatogenesis from cryopreservered testicular issue for restoration of fertility in males. ICMR
  • Principal Investigator
  • 24
  • Completed   Sponsored
Design and fabrication on 3D Scaffolds & Tissue Engineering Testicular Construct for in-Vitro Spermatogenesis ICMR
  • Principal Investigator
  • 36
  • Completed   Sponsored
Molecular mechanism of Pluripotency in Testicular stem cells - An Insilico Approach. ICMR
  • Principal Investigator
  • 24
  • Completed   Sponsored
Creation of Bioinformatics Infrastructure facility for the promotion of Biology teaching through Bioinfoematics (BTBI) scheme of BTIS-NET. DBT
  • Principal Investigator
  • 156
  • Completed   Sponsored
In vitro spermatogenesis as a method to by pass pre and post meiotic barriers to spermatogenic process and restoration of firtility ICMR
  • Principal Investigator
  • 36
  • Completed   Sponsored
Analysis of spermatozoal RNA and its functional relevance to fertility CSIR
  • Principal Investigator
  • 36
  • Completed   Sponsored
Testicular Stem Cell-mediated Transgenesis for production of Granulocyte Colony Stimulatinjg factor(G-CSF) DBT
  • Principal Investigator
  • 36
  • Completed   Sponsored
ERASMUS MUNDUS(HERITAGE) EDUCATION AUDIOVISUAL AND CULTURE EXECUTIVE AGENCY,FRANCE
  • Principal Investigator
  • 48
  • Completed   Sponsored

Total Publications: 125

J. H. Hwang, M. K. Gupta, C. Park, Y. B. Kim, and H. T. Lee,"Establishment of major histocompatibility complex homozygous gnotobiotic miniature swine colony for xenotransplantation", Animal Science Journal, vol.86, no.4, pp.468 - 475, John Wiley & Sons, April 2015, 10.1111/asj.12312       Article

S. H. Lee, M. K. Gupta, Y. T. Ho, T. Kim, and H. T. Lee,"Transgenic chickens expressing human urokinase-type plasminogen activator", Poultry Science, vol.92, no.9, pp.2396 - 2403, Oxford Academic, September 2013, 10.3382/ps.2013-03223       Article

M. K. Gupta, Z. C. Das, Y. T. Heo, Jin. Y. Joo, Hak. J. Chung, H. Song, Jae. H. Kim, Nam. H. Kim, H. T. Lee, Dae. H. Ko, and S. J. Uhm,"Transgenic chicken, mice, cattle, and pig embryos by somatic cell nuclear transfer into pig oocytes", Cellular Reprogramming, vol.15, no.4, pp.322 - 328, Mary Ann Liebert, Inc. 2013, 10.1089/cell.2012.0074       Article

K. T. Lim, M. K. Gupta, S. H. Lee, Y. H. Jung, D. W. Han, and H. T. Lee,"Possible involvement of Wnt/ß-catenin signaling pathway in hatching and trophectoderm differentiation of pig blastocysts", Theriogenology, vol.79, no.2, pp.284 - 290, Elsevier, January 2013, 10.1016/j.theriogenology.2012.08.018       Article

Ym. Kim, Sj. Uhm, M. K. Gupta, Js. Yang, J. G. Lim, Zc. Das, Yt. Heo, Hj. Chung, Ik. Kong, Nh. Kim, Ht. Lee, and Dh. Ko,"Successful vitrification of bovine blastocysts on paper container", Theriogenology, vol.78, no.5, pp.1085 - 1093, Elsevier, September 2012, 10.1016/j.theriogenology.2012.05.004       Article

Computer Aided Drug Designing and Molecular Dynamics Simulations Biotechnology and Medical Engineering (Short-term Course)
Training Program on Multi-Omics for Biomarker Development Biotechnology and Medical Engineering (Short-term Course)
Training Program on Genomic and Proteomic Analysis for Developing Biosimilars (GPP-2019) Biotechnology and Medical Engineering (Short-term Course)
Gene Analysis and Manipulation for Industrial Expression of Proteins Biotechnology and Medical Engineering (Short-term Course)
Training Program on Gene Analysis and Manipulation for Industrial Expression of Proteins Biotechnology and Medical Engineering (Short-term Course)
Short Term Training Program on Applications of Bioinformatics in Biotechnology Biotechnology and Medical Engineering (Short-term Course)

  • BM2005 : Biostatistics {Theory}
  • BM201 : Basic Medical Science {Theory}
  • BM3101 : Genetic Engineering {Theory}
  • BM341 : Genetic Engineering {Theory}
  • BM343 : Bioinformatics {Theory}
  • BM344 : Genetic Engineering {Theory}
  • BM390 : Special Topics in Biotechnology and Medical Engineering (Biotechnology in Human Health) {Theory}
  • BM4102 : Animal Biotechnology {Theory}
  • BM601 : Anatomy and Physiology {Theory}
  • BM622 : Stem Cell Engineering {Theory}
  • BM627 : Cryo-Tissue Engineering {Theory}
  • BM6644 : Animal Biotechnology {Theory}
  • BM681 : Special Topics in Biotechnology and Medical Engineering – I {Theory}
  • BM682 : Special Topics in Biotechnology and Medical Engineering - II {Theory}
  • BM273 : Basic Medical Science Laboratory {Practical}
  • BM274 : Analytical Biotechnology Laboratory {Practical}
  • BM368 : Product Development Laboratory – II {Practical}
  • BM370 : Bioinformatics Laboratory {Practical}
  • BM3708 : Analytical Techniques in Biotechnology Laboratory {Practical}
  • BM3711 : Genetic Engineering Laboratory {Practical}
  • BM378 : Computer Aided Drug Design Laboratory {Practical}
  • BM381 : Bioinformatics Laboratory {Practical}
  • BM394 : Special Laboratory in Biotechnology&Medical Engg.–II {Practical}
  • BM4705 : Bioinformatics Laboratory {Practical}

Ph.D. Students [8]
Detailed Study on The Molecular Mechanism of Pluripotency and Reprogramming in Testicular Stem Cells - In Silico Approach
Guttula Praveen Kumar
Enrolled: Jan 2015
Graduated :  Aug 2021
Supervisor
Cryopreservation of Testicular Cells and Tissues by Solid Surface Vitrification
Tanushree Patra
Enrolled: Aug 2014
Graduated :  Dec 2021
Supervisor
Analysis of RNA Population in Goat Spermatozoa
Bijayalaxmi Sahoo
Enrolled: Jul 2015
Graduated :  Oct 2023
Supervisor
Polyvinyl Alcohol-Polyvinyl Pyrrolidone and Polycaprolactone based Matrices for Cardiac Tissue Engineering Applications
Pallavi Pushp
Enrolled: Jul 2012
Graduated :  Sep 2020
Supervisor
Chitosan-based Bioactive Nanofibrous Hemostatic Agent for Emergency Care
Balaram Mishra
Enrolled: Jul 2019
Thesis Submitted
Supervisor
Tissue Engineering (Reproductive)
Nimbal Kalita
Enrolled: Aug 2021
Continuing
Supervisor
Hemostatic Biomaterials
Samadrita Roy
Enrolled: Aug 2022
Continuing
Co-Supervisor
Analysis and Quantification of Physical Fatigue in Automobile Drivers: A Biomedical Approach
Bibhukalyan Prasad Nayak
Enrolled:
Graduated :  2016
Supervisor

Awards And Honours
  • Subject Expert, Union Public Service Commision (UPSC), Govt. of India,   2023
  • Expert, National Board of Accreditation (NBA), India,   2023
  • Chairman, Local Organizing Committee, Central Seat Allocation Board-2023 (CSAB-2023),   2023
  • Member, Technical Committee, Centralized Counseling for M.Tech/M.Plan – 2023 (CCMT-2023),   2023
  • Member, Technical Committee, Centralized Counseling for M.Tech/M.Plan – 2022 (CCMT-2022),   2022
  • Chairman, Local Organizing Committee, Central Seat Allocation Board-2022 (CSAB-2022),   2022
  • Associate Editor (Livestock Genonics), Frontiers in Genetics,   2022
  • Associate Editor (Livestock Genonics), Frontiers in Veterinary Science,   2022
  • Editorial Board Member, Frontiers in Cell and Developmental Biology,   2022
  • Subject Expert (Animal Biotechnology), National Testing Agency (NTA), Govt. of India,   2022
  • Member, Technical Committee, Centralized Counseling for M.Tech/M.Plan – 2021 (CCMT-2021),   2021
  • Subject Expert, All India Council for Technical Education (AICTE), Govt. of India,   2020
  • Member, Core Committee and Technical Committee, Centralized Counseling for M.Tech/M.Plan – 2020 (CCMT-2020),   2020
  • MHRD-NPIU appointed Mentor for NIT Meghalaya,   2019
  • MHRD-NPIU appointed Mentor for IIIT Manipur,   2019
  • Chairman, Local Organizing Committee and Technical Committee, Centralized Counseling for M.Tech/M.Plan – 2019 (CCMT-2019),   2019
  • Performance Auditor, Rajakiya Engineering College, Azamgarh,   2018
  • Expert Member, Technical Evaluation Committee, BIRAG-BIG, KIIT,   2018
  • Member, Expert Committee, Selection of Assistant Professors under TEQIP-III,   2018
  • Nominee, CPCSEA, MoEF&CC, GoI,   2017
  • Member, External Examiner Board, University of Malaya, Malaysia,   2017
  • Scientific Steering Committee and Executive Member, HERITAGE Network, Ecole Centrale de Nantes, France,   2017
  • Editorial Board Member, Journal of Animal Research (since 10.09.2011),   2017
  • Editorial Board Member, Indian Journal of Veterinary Science and Biotechnology (Since 10.02.2015),   2015
  • Vice-Chairman, LOC, Centralized Counseling for M.Tech/M.Plan – 2015 (CCMT-2015),   2015
  • Associate Editor (Biotechnology and Bioinformatics), Manthan (Since 06.06.2015),   2015
  • Executive Member, External Relations Committee, Council of Asian Science Editors (CASE),   2014
  • Data Auditor, TEQIP-II at NERIST, Arunachal Pradesh,   2014
  • Editorial Board Member, Progress and Communication in Science (Since 22.12.2013),   2013
  • Editorial Board Member, The Open Gene Therapy Journal (Year 2013),   2013
  • Editorial Board Member, ISRN Developmental Biology (Since 01.06.2012),   2012
  • Editorial Board Member, Journal of Krishi Vigyan (Since 12.2012),   2012
  • Scientific Steering Committee Member, Asian Reproductive Biotechnology Society (ARBS),   2012
  • Editorial Board Member, International Journal of Zoological Research (Past: 2007-2012),   2007
  • Editorial Board Member, Asian Journal of Developmental Biology (Past: 2007-2012),   2007
  • Editorial Board Member, Journal of Biological Sciences (Past: 2007-2012),   2007
  • Editorial Board Member, International Journal of Agricultural Research (Past: 2007-2012),   2007
  • Editorial Board Member, Asian Journal of Animal and Veterinary Advances (Past: 2007-2012),   2007
  • Best Research Award, Korean Society of Animal Reproduction (KSAR),   2005
  • Seoul Science Fellowship, Govt. of South Korea,   2004
  • Dr. S. N. Luktuke Award, Indian Society for Study of Animal Reproduction (ISSAR),   2003
  • University Gold Medal, TANUVAS University,   2003
  • Junior Research Fellow, Indian Council of Agriculture Research (ICAR),   2001
  • Pfizer’s Best Veterinary Clinician Award,   2001
  • Dr. B. Nandakumaran Memorial Gold Medal Award,   2001
  • Partha Sarathi Das Memorial Award,   2001
  • Dr. Y.V.B.Gangadhara Rao Memorial Gold Medal Award,   2001
  • Pondicherry University Prize and Gold Medal,   2001
  • PTA Merit Scholarship Awards,   2001
Memberships / Fellowships
  • Board Member, Animal Welfare Board of India (AWBI), Govt. of India,   2024
  • Member, Committee for Control and Supervision of Experiments on Animals (CCSEA), Ministry of Fisheries, Animal Husbandry and Dairying, Govt. of India,   2024
  • Fellow, National Environmental Science Academy (FNESA), India,   2023
  • Fellow, National Academy of Agricultural Sciences (FNAAS), India,   2022
  • Fellow, Indian Association for the Advancement of Veterinary Research (FIAAVR),   2022
  • Associate Fellow, National Academy of Veterinary Sciences (FNAVS), India,   2022
  • Fellow, National Academy of Dairy Sciences (FNADS), India,   2022
  • Fellow, National Academy of Biological Sciences (FNABS), India,   2022
  • Life Member, National Environmental Science Academy (NESA),   2021
  • Member, IEEE, USA,   2021
  • Member, IEEE Engineering in Medicine and Biology Society, USA,   2021
  • Fellow, Royal Society of Biology (FRSB), UK,   2020
  • Life Member, Association of Mastitis,   2020
  • Member, Society of Cryobiology, USA,   2019
  • Laboratory Animal Scientists’ Association (LASA),   2019
  • Life Member, Society for Veterinary Sciences and Biotechnology (SVSBT),   2015
  • Life Member, Biotech Research Society (BRS),   2014
  • Member (Senior), International Association of Computer Science and Information Technology (IACSIT),   2014
  • Member, International Society for Research and Development (ISRD),   2014
  • Life Member, Society of Biological Chemists (SBC),   2014
  • Life Member, Society for Reproductive Biology and Comparative Endocrinology,   2014
  • Life Member, Society of Biological Scientists of India (SOBSI),   2014
  • Life Member, Indian Society of Cell Biology (ISCB),   2014
  • Life Member, Indian Society for Study of Reproduction and Fertility (ISSRF),   2014
  • Founding Member, Council of Asian Science Editors (CASE),   2014
  • Member, Asia Pacific Initiative on Reproduction (ASPIRE),   2014
  • Fellow, Academy of Environment and Life Science (FAELS),   2013
  • Fellow, Society for Applied Biotechnology (FSAB),   2013
  • Life Member, National Academy of Biological Sciences (NABS),   2013
  • Life Member, Biomedical Engineering Society of India (BMESI),   2013
  • Associate Member, Eastern Mediterranean Health Genomics and Biotechnology Network (EMGEN),   2013
  • Member (Senior), Asia-Pacific Chemical, Biological and Environmental Engineering Society (CBEES),   2013
  • Life Member, Society for Tissue Engineering and Regenerative Medicine (STERMi),   2013
  • Life Member, Indian Association for the Advancement of Veterinary Research (MIAAVR),   2013
  • Life Member, Society of Krishi Vigyan,   2012
  • Executive Member, Bihar Foundation, South Korea Chapter,   2010
  • Life Member, Asian Reproductive Biotechnology Society (ARBS),   2007
  • Life Member, Indian Society for Study of Animal Reproduction (ISSAR),   2002