Course Details
Subject {L-T-P / C} : CY4112 : Chemistry of Biological Relevance { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Rabindra Kumar Behera
Syllabus
Chemical Evolution: The Beginning of Life O2, N2 and H2O: Physical and Chemical Properties DNA, RNA and Protein: Structure, Function and Synthesis Cell and Its Compartments: Role of lipid Membrane, Ion Channels and Pumps, Signal Transduction and Heart/Muscle Contraction Chemistry of ATP, NAD(P)H, Glucose: Photosynthesis and Respiration Heme and NO: Red Blood Cell and The Vasodilator Coupling the Reactions: Making Non-spontaneous to spontaneous Enzymatic Reactions and its Kinetics: Regulating the metabolism Dark Side of O2: Oxidative Stress (Kiss of Death) Biochemical and Biophysical Methods: to study Biomolecules and their interactions.
Course Objectives
- To understand the basic chemical and physical principles that underlie the biological functions.
- To learn advanced techniques to characterize the complex biological processes
Course Outcomes
Students will understand the basic chemical and physical principles that underlie the biological functions. What are the molecules (organic and inorganic) that are needed for life? How large biological macromolecules synthesized from their building blocks. Finally the course will help them to learn advanced techniques to characterise and study these complex biological processes.
Essential Reading
- Alberts, B., Johnson,A., Lewis, J., and Enlarge, M., Molecular Biology of the Cell, Garland Science. , 5th Edition, 2008
- V. Voet and J. G. Voet, Biochemistry, John Wiley, New York , 4th Edition, 2004
Supplementary Reading
- Sheehan, D., Physical Biochemistry: Principles and Applications, Wiley Blackwell. , 2nd Edition, 2010
- Reginald H Garrett, Charles M Grisham, Biochemistry, Cengage Learning , 4th Edition, 2010.
Journal and Conferences
- Science Magazine (https://www.science.org/)