Course Details
Subject {L-T-P / C} : CY4104 : Spectroscopic Methods of Analysis { 3-1-0 / 4}
Subject Nature : Theory
Coordinator : Dr. Bimalendu Adhikari
Syllabus
Electromagnetic radiations: Types of molecular energy and molecular spectroscopy
Infrared Spectroscopy: Basic theory, instrumentation and application to functional group determination. UV-Visible Spectroscopy: Basic concepts, instrumentation and applications Mass Spectrometry: Principle, Instrumentation and applications, Fragmentation pattern of organic compounds, McLafferty rearrangement NMR Spectroscopy: Basic principles, Chemical shift, Spin-Spin Coupling, Coupling Constant, NOE, 13C NMR, DEPT NMR, heteronuclear coupling, Pulse NMR spectroscopy and techniques, relaxation time and their importance, determination of relaxation times, Temperature dependent NMR and molecular dynamics, Elementary ideas on 2D NMR spectroscopy (COSY, NOESY, HMQC, HSQC, HMBC), Extension to other nuclei (19F, 31P etc).
Structure elucidation of Organic Compounds: Use of spectroscopic techniques for structure determination and other applications.
Optical rotatory dispersion and Circular dichroism: Definition, deduction of absolute configuration, octant rule for ketones.
Course Objectives
- Students will learn basic spectroscopic methods for analysis of organic compounds.
- Student will be able to derive the structure of the organic compound based on different spectroscopy data.
Course Outcomes
1)The students will able to understand the basic spectroscopic methods used for the analysis of organic compounds. <br />2) Detailed discussions on principles, instrumentations and applications of these techniques will be carried out.
Essential Reading
- D. C. Pavia, G. M. Lampman, G. S. Kriz, Introduction to Spectroscopy, THOMSON , 3 rd edition 2007
- J. Mohan, Organic Spectroscopy, Narosa Publishing House , 2004
Supplementary Reading
- . B. H. Williams, I. Flemming,, Spectroscopy Methods in Organic Chemistry, ., McGraw Hill, , 2005
- Bessler and Silverstein, Spectroscopy of Organic Compounds, JOHN WILEY , 2001