National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : BM3709 : Bioprocess Optimization Laboratory { 0-0-2 / 1}

Subject Nature : Practical

Coordinator : Prof. Kasturi Dutta

Syllabus

Full factorial designs for measuring all possible interactions, Fractional factorial designs for measuring limited interactions, Analysis of Variance, Generate an experimental design using excel, carry out and analysis of the experimental designs using excel, Generate Central composite designs (CCDs) with the Statistics and Machine Learning Toolbox function, Generate Box-Behnken designs (BBDs) with the Statistics and Machine Learning Toolbox function, Visualize results of experimental designs using Design of Experiments (DOE) plots such as interaction plot, main effects plot, multi variable plots. Demonstration of design expert and xlstat softwares. Demonstration of RSM in matlab.

Course Objectives

  • Knowledge about optimization techniques

Course Outcomes

The student will learn the optimization techniques used in bioprocess

Essential Reading

  • Myers, R.H., D. C. Montgomery, C. M. Anderson-Cook, Response Surface Methodology: Process and Product Optimization Using Designed experiments, wiley, 2015.
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Supplementary Reading

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